Tricyclic antidepressants are the antidepressant drugs that act by blocking the reuptake of norepinephrine and serotonin hormones and thus making more of those substances available to act on the receptors in the brain. Since their discovery in the 1950s, tricyclic antidepressants have been used to treat mental depression and like any other anti-depression drug; they were prescribed to reduce symptoms such as extreme sadness, loneliness, and lack of energy. They may also produce many unwanted side effects like dizziness, drowsiness, headache, nausea, or in rare cases - blurred vision, hallucinations, arrhythmia etc. There are some Tricyclic antidepressant testing kits available in the market, which work on the principles of enzyme-linked-immunosorbent serologic assay which is an assay that relies on an enzymatic conversion reaction and is used to detect the presence of specific antigens, tricyclic antidepressant in this case. They come in the form of various urine test strips with antigen specific antibodies coated onto them.






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